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It is crucial for future research to determine the proportion of ferroptosis in formononetin -mediated breast cancer cell death and to explore the cross talk between various PCDs, as this represents a significant avenue for further investigation

In addition, many tumors can obtain access to blood supply through vascular co-option, bypassing the need of tumor angiogenesis [5]

Thus, our study provides additional substantiation for the appropriateness of this model in simulating the environment wherein the replanted grafts reside post-transplantation, and investigating the mechanisms governing cell death