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Similarly, lentiviral overexpression of GPx-1 confers a beneficial effect to neuroblastoma cells in culture and to nigral dopaminergic neurons exposed to 6-hydroxydopamine in vivo (308)

3) and a split-thickness skin graft was performed

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showed that curcumin administration (8 g/day) with melphalan (4 mg/m 2 ) and prednisone (40 mg/m 2 ) for 28 days reduced the levels of NF-B, VEGF, TNF-, and IL-6 in myeloma ( n = 33)

Additionally, metabolomics holds the potential to identify innovative targets for therapeutic intervention, paving the way for novel treatment strategies (Table 3