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Surprisingly, expression of acyl-CoA:cholesterol acyltransferase 1, the enzyme that mediates the esterification of cholesterol to cellular cholesteryl esters was increased 24-fold in WAT and 58-fold in BAT

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(2001) investigated AOD9604 in obese Zucker rats and observed that chronic administration was associated with reduced body weight gain without changes in IGF-1 levels or glucose tolerance, distinguishing its activity profile from that of full-length growth hormone [1]