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One cause of such a cytokine storm is an imbalance of the ratio between ACE1 (the pro-inflammatory mediator) and ACE2 (the anti-inflammatory mediator)

Cell-mediated immune responses with antigen-specific T cells decrease in COVID-19 patients and affect viral clearance from infected host cells 211

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In addition, these researchers showed that giving antibiotics to normal mice to wipe out their gut bacteria eliminated the production of TMA for either L-carnitine or choline and so also stopped TMAO production.The type of bacteria living in our digestive tracts are largely dictated by our long-term dietary patterns
