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Description
In multiple rodent models of chronic stress (a shared risk factor for major psychiatric illnesses), administration of LAC leads to a rapid and persistent antidepressant-like response by increasing histone acetylation and expression of key genes, including mGlu2 receptors and the downstream brain-derived neurotrophic factor BDNF [27, 30, 34,35,36,37]

[Google Scholar] 72.Diehl E.E., Haines G.K., Radosevich J.A., Potempa L.A

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Acetyl-L-carnitine should be taken continuously over a minimum period of 3 to 6 months, to ensure the optimal build-up of vital substances

(1963): Carnitine and its role in fatty acid metabolism
