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Detoxification: GSH participates in the detoxification of xenobiotics and endogenous metabolites through conjugation and excretion pathways

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TGF-1 induced EMT increases the intracellular levels of unstable iron and ROS, and the elevated iron content and oxidative stress in cells undergoing EMT make them more susceptible to ferroptosis

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Consequently, TK modelling still holds significant potential to make impactful contributions in the field, supported by the growing availability of diverse in silico resources accessible to the scientific community (Madden et al