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10.1073/pnas.1120210109 Proc

Zinc deficiency coupled with altered immune response, as occurring in ageing, leads to an increased susceptibility for some age-related diseases (Vasto et al

Glutathione injections are used to boost levels of this essential molecule, promoting overall health and vitality

However, the significance of this effect is unclear as the authors did not include comparator groups without dextran sulfate sodium treatment, which would be needed meaningfully assess the effect of the treatment on circadian rhythmicity

For HMGA1 knockdown, the following siRNA sequences were employed: si HMGA1 #1 (5-CAACTCCAGGAAGGAAACCAA-3), si HMGA1 #2 (5- CCAGCGAAGTGCCAACACCTA-3)