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In yeast, mitochondria-associated degradation (MAD)analogous to ERADensures proteostasis by extracting, ubiquitinating, and degrading misfolded mitochondrial proteins in the cytosol

Negative scans are some of the easiest operations

Mild site tenderness is possible but short-lived

Its tolerability profile supports its use in patients with altered bowel motility, though we have no objective data confirming benefit in CIRS
