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Celecoxib-induced gastrointestinal, liver and brain lesions in rats, counteraction by BPC 157 or L-arginine, aggravation by L-NAME
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By inhibiting NNMT, it leads to an increase in intracellular levels of NAD+ (nicotinamide adenine dinucleotide), a critical coenzyme for cellular metabolism and mitochondrial energy production
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We performed RNA-sequencing in MP group and MP + GDF11 treatment group, the result showed the expression level of NOS3 and angiogenesis biomarkers was increased in GDF11 supplementation group (Fig
