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There is no one best treatment for hyperpigmentation since it depends on the type of discoloration and which layer of skin is affected
10.1016/s0028-3908(02)00061-8 Neuropharmacology 18 BieB.PanZ
In laboratory and educational research, peptide blends are often used to explore complex biological responses that involve more than one pathway
Further, NICE and the BNF says that if there are neurological symptoms present, then every other day injections are the recommended treatment, so all the points you make about B12 being stored and sufficient are not really relevant
