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The Th1 branch of the immune system creates both the pro-inflammatory state mentioned previously, and cytokines (pro-inflammatory proteins)

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10.1016/j.micron.2009.08.010 Micron

Excessive ROS production amplifies the recruitment of proinflammatory cytokines, thereby inducing inflammation, oxidative stress, and lipid peroxidation

A general rule of thumb is to lower yourself down until your arms are roughly parallel to the ground and your forearms are vertical so that your elbows form 90 degree angles, but there is no universal standard
