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Although the amyloid hypothesis of AD remains controversial, variants leading to altered APP processing have devastating effects on carriers and their families, thereby warranting further research in this area and personalized strategies that target aberrant APP processing (Kametani and Hasegawa, 2018)

Ouders en onderzoekers wisten niet wie wat kreeg dat maakt de resultaten betrouwbaarder

GST-Gid7 was purified by glutathione affinity chromatography followed by incubation overnight at 4 C with TEV protease at a concentration of 0.05 mg/ml to remove the GST tag

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The placebo group received a 5%-dextrose multielectrolyte iv- infusion (GLUCIDION G5, B