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It does not eliminate uncertainty, but it substantially reduces it, and that is exactly what the committee is being asked to evaluate

Oxidative stress and high-density lipoprotein function in Type I diabetes and end-stage renal disease

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there is also the relaxation of large vessels (ex vivo), mainly by acting on vascular endothelial cells but also on vascular smooth muscle cells [93,94])

Consequently, this regulation promotes endothelial cell proliferation, migration, and lumen formation, which are crucial for angiogenesis