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It is often said that B12 supplements do not cause problems, that there is no limit, that you can take as much as you want, that if you take too much it is eliminated in urine because it is water-soluble

Pharmacokinetic Profile Route of Administration Oral Half-Life 6-8 hours Route of Administration: Oral, Intravenous Dosing Frequency: Once per day Half-Life: ~6-8 hours Formulation & Handling Soluble in saline

Understanding Vitamin B12 and Its Importance Vitamin B12, known scientifically as cobalamin, is essential for maintaining nerve tissue health, brain function, and the production of red blood cells

doi: 10.1016/j.cell.2012.03.037

Diabetic Med