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Elevated ROS levels can cause DNA damage, leading to mutations and genomic instability
Cephalalgia 38 , 17591764 (2018)
NNMT is overexpressed in adipose tissue and various cancer cell lines, and its inhibition has been studied as a strategy to increase intracellular NAD+ levels, enhance one-carbon metabolism, and reduce adipogenesis in preclinical models
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[DOI] [PMC free article] [PubMed] [Google Scholar] 124.Alaaeldin R., Mohyeldin R.H., Bekhit A.A., Gomaa W., Zhao Q.L., Fathy M
