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Description
In addition to the mitochondrial sources, the NOX enzyme system (located on the plasma membrane, endoplasmic reticulum, and endocytosome membrane) catalyzes electron transfer from NADPH to O 2 to produce O 2
Rig-I detects infection with live listeria by sensing secreted bacterial nucleic acids
Downstream signaling triggers the formation of the ROS, OH
Highrisk genes such as DISC1, dysbindin and NRG1 are all modulators of the AKTGSK3 signaling pathway [34]
Endothelial cells can generate ATP in anaerobic conditions and store oxygen, and this paradox brings decreased ROS levels and rapid ATP generation [53]
