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How I Met Your Mother star Neil Patrick Harris made a major splash in the role, winning a Tony Award in June, and a literal one, spitting water at an annoying audience member during one performance

Cochrane Database Syst Rev 2015;2015:CD009580.ArticlePubMedPMC 50

While it is commonly used to enhance cognitive performance and mitigate the effects of stress, its role in addressing caffeine jitters is more complex and theoretical

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Moreover, the focus of the Cerebral Functions domain in the EDSS does not include an extensive analysis of fatigue and its correlates in the patient's life and activities of daily living (Cadavid et al., 2019