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nonclinical studies: A guide for regulatory affairs students

doi: 10.1101/cshperspect.a029082 192 SabatinoJ

Quantification of average fluorescence intensities at these compartments confirmed a much higher Golgi and a lower PM localization of Go-Nt 7 compared to Go-Nt 31 and Go (Fig

In an additional set of experiments that focused on the determination of intracellular localization of pigment uptake, cells were exposed to C-phycocyanin (0.2 ) for 1 and 20 h, and MitoTracker Green FM (100 nM) and LysoTracker Green DND-26 (75 nM) (Molecular Probes, Life Technologies, Carlsbad, CA, USA) for staining of mitochondria and lysosomes, respectively

Collectively, these findings present strong evidence supporting an association between the anxiolytic and stimulant effects of alcohol, hinting at potential shared underlying mechanisms
