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The evolution of iron chelators for the treatment of iron overload disease and cancer

Adiponectin, for instance, does not affect circadian clock gene expression in some peripheral tissues, but its knockout alters the circadian rhythm of glucose and lipid metabolism 115

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Canton-S, w iso31 (from Dr Alex Gould), and w Dah (from Dr Linda Partridge) flies were used as control strains

This critical data point proves that reducing the intake of specific fermentable carbohydrates and inflammatory triggers directly decreases endogenous histamine production and mast cell activation in the gut