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Although there seem to be no recorded cases of Vitamin B12 overdose, it may not be a good idea to get B12 injections during pregnancy

A subsequent study identified the compound N-(4-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)phenyl)acetamide as a notable SARM1 inhibitor, which demonstrated significant efficacy in a mouse model of CIPN (Fig

That is a very different statement from they do nothing. It means: The mechanistic rationale is real

Additionally, Clark points out that gastrointestinal conditions, such as celiac disease, Crohns disease and ulcerative colitis, can impair absorption in the small intestines, contributing to low B12 levels

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