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Uremic toxins cause endothelial damage, whereas NAC therapy reduces NF-B upregulation, which requires reactive oxygen species (203)

1 Introduction Fibrotic disease is a widespread disease that critically threatens public health, mainly including pulmonary fibrosis, liver fibrosis, renal fibrosis, myocardial fibrosis, peritoneal fibrosis, and other diseases

In the light of this, consideration deficiency in A1AT is a possible pathogenic cofactor in ANCA-associated vasculitis (AAV) (97)

Post-injury healing may enhance through improved tissue quality

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