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In this way, ALKBH5 directly downregulates CHAC1 and contributes to ferroptosis resistance in gastric cancer cells ( 2.3.2 CHAC1-mediated ferroptosis in cancer and neurological disorders: mechanisms and therapeutic implications Generally, cancer cell lines show a high variety in terms of sensitivity toward ferroptosis (Yang et al., 2014)

Choi SH, Park KW, Na DL, Han HJ, Kim EJ, Shim YS, Lee JH (2011) Tolerability and efficacy of memantine add-on therapy to rivastigmine transdermal patches in mild to moderate Alzheimers disease: A multicenter, randomized, open-label, parallel-group study