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For functional medicine practitioners and researchers interested in this area, understanding what the evidence actually supports versus what remains speculative is the critical starting point

Vitamin B12 (the same vitamin B12 that we rely on, as humans, to stay healthy) can be provided to livestock like sheep, chickens, and pigs in liquid or injectable form

However, the requirement for HSL phosphorylation has recently been challenged as studies by the Granneman group elegantly show that direct activation of PNPLA2 in the absence of PKA stimulation is sensitive to HSL inhibition, suggesting that PNPLA2-mediated generation of DAG is sufficient to promote HSL activity (49)

This simple step prevents the introduction of bacteria and other contaminants

Lessons in biology from patients with inborn errors of vitamin B12 metabolism