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Bai F, Deng Y, Li L, Lv M, Razzokov J, Xu Q, Xu Z, Chen Z, Chen G, Chen Z

Unlike apoptosis, which involves caspase activation and nuclear fragmentation, ferroptosis is initiated by iron accumulation and lipid peroxidation, resulting in membrane rupture without caspase involvement ( This review aims to comprehensively analyze recent advances in understanding ferroptosis mechanisms in CHD and evaluate emerging clinical intervention strategies

So, I mean, we've got this conundrum of we're never activating these stress response pathways that we're supposed to activate

doi: 10.1016/j.fitote.2018.05.010

The results showed that the treated nematodes exhibited no obvious differences in size or morphology compared with the control group, and no significant mortality was observed