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3 Ferroptosis has been implicated in several liver diseases, such as drug-induced liver injury, ischemia-reperfusion injury, chronic liver disease, and hepatocellular carcinoma

However, based on our tLRRK2 data, and the literature on using LRRK2 inhibitors 32 , we do not expect decreased functional LRRK2 to present with these phenotypic effects

Jia W, Liang S, Cheng B,Ling C

Additionally, another study conducted in 2020 found that apart from directly causing cell death, DDC can effectively stimulate immunogenic cell death (ICD) in cancer cells, leading to the modification of the immunosuppressive tumor microenvironment (TME)