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Macrophages and neutrophils are necessary for ER stress-induced cell loss

doi: 10.1074/jbc.M412802200 68 CondamineT.MastioJ.GabrilovichD

FIGURE 3 7.1 Flavonoids: multitarget antioxidants and metabolic regulators Flavonoids exert hepatoprotective effects through synergistic mechanisms that include direct ROS scavenging, activation of antioxidant pathways, and metabolic regulation

Mehmood, S

In a phase II clinical trial (NCT02644369), it was found that an increase in serum choline levels (cholineC3) at week 7 in patients receiving pembrolizumab treatment was significantly associated with better progression-free survival (PFS) and showed a trend of improvement in overall survival (OS)
