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Clinical studies have investigated its potential in age-related mitochondrial dysfunction

[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Vich Vila A, Imhann F, Collij V, Jankipersadsing SA, Gurry T, Mujagic Z, Kurilshikov A, Bonder MJ, Jiang X, Tigchelaar EF, Dekens J, Peters V, Voskuil MD, Visschedijk MC, van Dullemen HM, Keszthelyi D, Swertz MA, Franke L, Alberts R, Festen EAM, Dijkstra G, Masclee AAM, Hofker MH, Xavier RJ, Alm EJ, Fu J, Wijmenga C, Jonkers DMAE, Zhernakova A, Weersma RK

Studies in mice, rats, rabbits, and dogs found no severe toxic effects across a wide dose range from 6mcg/kg to 20mg/kg

MIC is the combination of Methionine, Inositol, and Choline

K., Alvarado, E., Yuan, H., Wu, H., & Chen, W