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Low Birth Weight : Inadequate levels of Vitamin B12 during pregnancy can result in the baby being born with low birth weight

Pregnant women require 1.5 g daily (the same as non-pregnant adults), whilst breastfeeding mothers need 2.0 g to support both their own requirements and those of their infant through breast milk

But PURPOSE 1 and PURPOSE 2 are the first clinical trials to test it for HIV prevention

Monitoring and follow-up Monitor clinically and repeat tests as indicated by the underlying condition Ongoing monitoring of liver function, renal function, and FBC as clinically indicated Regular review in primary care or specialist clinics for underlying conditions Patient advice: Patients should understand that elevated B12 is a marker requiring investigation rather than a condition requiring direct treatment

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