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[15] Serious but infrequent events-such as angioedema, bronchospasm, hypotension, or urticaria-reflect IgE-mediated hypersensitivity and may require desensitization or substitution with hydroxocobalamin

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[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Schndorf DC et al

If you or your child develops any warning signs, monitoring the situation closely and seeking immediate medical attention if symptoms worsen or persist is important