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Prostaglandins Other Lipid Mediat 122:5463 Crews F, He J, Hodge C (2007) Adolescent cortical development: a critical period of vulnerability for addiction

Under normal circumstances, NRF2 forms a complex with its inhibitory protein, Keap1 which regulates the stability and nuclear translocation of NRF2, thereby controlling its activity

Hormesis is an example of where exposure to a low dose of a chemical agent or environmental factor is beneficial but damaging at higher doses and where modest increases in ROS can activate positive cellular responses

Sci Rep 15 , 35529 (2025)

The absence of sensitive and accurate outcome measurements in MS has also slowed the development of neuroprotective medicines