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10.1002/jcp.21706 185
The subtle synaptic and functional changes within the hippocampus underlie the majority of age-related memory impairment (Morrison and Baxter, 2012)
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The proposed primary mechanism involves augmentation of hepatocyte growth factor (HGF) / c-Met receptor signaling, with downstream activation of MAPK, PI3K-Akt and the canonical synaptic-protein-synthesis machinery [2]
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