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[DOI] [PubMed] [Google Scholar] 61.Aimo L., Mackenzie G.G., Keenan A.H., Oteiza P.I

TXNIP, a novel key factor to cause schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression

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In addition to being a harmful reactive compound, 4-HNE can regulate the affinity of activator protein-1 (AP-1) to DNA, promoting or inhibiting NF-B activation and, therefore, the inflammatory process