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To establish connection with the NO-system, L-NAME (5.0 mg/kg) (worsening) and L-arginine (200.0 mg/kg) (effective only with blunted NO-synthesis, but not alone) were given intraperitoneally alone or in combination (d-arginine 200.0 mg/kg was not effective, data not shown)

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Your doctor may be able to suggest the necessary dietary changes for you

in cases of chronic disease: half the dose at intervals of 1 2 weeks or less

Common doses are 200 to 500 micrograms once or twice a day, for 2 to 6 weeks