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In a recent study, Hu et al

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149 Metabolic Health A large study that used data from 5,189 middle-aged and older adults (2,171 men and 3,018 women) collected over a median of 10.9 years indicated lower DHEA-S and DHEA levels were associated with an increased risk of developing type 2 diabetes in both men and women

Because of the above limitations, allopurinol is often used as the drug of choice in a patient where lowering uric acid is the goal, but there remains a place for probenecid in the armamentarium (collection of medicinal resources) to manage gout
