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Skin purging is usually a temporary phase and will improve with continued use of the product
adding around 4 - 4.5 % transcutol p provided 40 % In-vitro release in 4 hrs and at least 60 % In-vitro release in 8 hrs
The organic phase was washed three times sequentially with saturated NaHCO 3 (aq), 0.1 M HCl, and saturated NaCl (aq), respectively
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