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165 ROS also interact with calcium signaling at the mitochondrialER interface, where Ca 2+ surges induce mitochondrial swelling and rupture via disrupted ion exchange and adenine nucleotide translocase (ANT) channel dysfunction

It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability

N-3 polyunsaturated fatty acids: relationship to inflammation in healthy adults and adults exhibiting features of metabolic syndrome

PLoS One 6:e21827

[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Brenchley J.M., Paiardini M., Knox K.S., Asher A.I., Cervasi B., Asher T.E., Scheinberg P., Price D.A., Hage C.A., Kholi L.M., et al