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It has completed phase 1b/2a trials as of January 2025
doi: 10.1080/21688370.2017.1373208
Pyruvate kinase M2 regulates the hypoxia-inducible factor 1-alpha (Hif-1) activity and IL-1 expression, being a key molecule to induce the Warburg effect in LPS-activated macrophages [117]
van RoesselSKasumovaGGVerheijJNajarianRMMagginoLde PastenaMet al
Infect Immun 74: 67616768
