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doi: 10.1007/s13668-025-00614-7

Miscellaneous/Less Common Chronic, debilitating musculoskeletal pain (especially associated with Hypermobile EDS)

In addition, mitochondria are also involved in HIF signaling by transmitting a large amount of metabolic stress to the HIF pathway

Forges T, Monnier-Barbarino P, Alberto JM, Guant-Rodriguez RM, Daval JL, Guant JL

The conserved catalytic site comprises a tetrad of amino acids: Sec46, Gln81, Trp136 and Asn147, the latter being directly involved in catalysis
