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doi: 10.1113/jphysiol.2007.135947

Different peptides target different wrinkle mechanisms: Neurotransmitter-inhibiting peptides (SNAP-8, Syn-Ake, Argireline) reduce the muscle contractions that create expression lines Carrier peptides (GHK-Cu) deliver minerals that catalyze collagen synthesis and repair UV-damaged tissue Signal peptides (Matrixyl, Palmitoyl Tripeptide) mimic collagen breakdown products to trigger new collagen production Multi-peptide complexes combine multiple mechanisms in a single formula for comprehensive wrinkle correction Retinol achieves anti-aging results partly through irritation causing controlled inflammation that stimulates repair

It enters a state called senescence, which is essentially cellular retirement

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