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What they found: Preventive administration: 70 to 85 % reduction in ulcer area Therapeutic administration: 60 to 75 % reduction And now the most interesting part: 10 ng/kg worked just as well as 10 g/kg Why it matters: If the molecule worked in a stoichiometric way (= simply blocking something piece by piece), a higher dose would necessarily produce a larger effect

(1992) Chronic exposure to morphine does not induce dependence at the level of the calcium channel current in human SH-SY5Y cells

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Lipotropic agents, particularly choline, have been shown to reduce liver fat accumulation, which is a key factor in metabolic health