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This context dependence also suggests that, when applying BCAA-related targets for disease intervention, it is necessary to distinguish between two different levels of regulatory modes: the mTOR-driven pro-inflammatory effects caused by enhanced BCAA uptake/transport, and the support provided by changes in BCAA catabolic flux to mitochondrial metabolism and reparative programs, so as to avoid conflating results obtained from different experimental systems

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10.1073/pnas.0701152104 Proc Natl Acad Sci U S A

It is important to mention that both the exposed and the non-exposed groups are not a migrant population but a stationary population

Research has revealed the presence of three homologs of the Nramp protein in rice: OsNramp1, OsNramp2, and OsNramp3