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Further screening of a gRNA multiplex library identified the unanticipated combination of knockdown of PYC1 (pyruvate carboxylase) and NTH2 (trehalose) which resulted in a 3-fold increase in titer of 227

Arachidonate 12-lipoxygenase (ALOX12) inactivation diminishes p53-mediated ferroptosis induced by ROS stress ( N1 -acetyltransferase 1 (SAT1) is a transcription target of p53, SAT1 expression induces lipid peroxidation and sensitizes cells to undergo ferroptosis upon ROS-induced stress, while knockout of SAT1 expression or pharmacologically inhibited ALOX15 partially abrogates p53-mediated ferroptosis (Ou et al., 2016)

The raw RRBS data have been deposited in NCBIs Gene Expression Omnibus (GEO) database under accession no

Reaction of aflatoxin B(1) oxidation products with lysine

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