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In clinical practices, combining conventional anti-tumor medications with adjuvant treatments has shown complementary and supplementary role that enhanced the safety and effectiveness while minimizing adverse effects of the applied therapeutic strategies, as evidenced by numerous clinical trials [277,278,279], namely on breast cancer (NCT03980509), prostate cancer (NCT03769766), cervical cancer (NCT04294836) and advanced pancreatic cancer (NCT00094445)

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