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Gastrointestinal Effects Digestive discomfort is the most frequently reported issue with acetyl-L-carnitine supplementation

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When carnitine is ingested, either through the diet or supplementation, part of it reaches the gut, where it can be metabolized by the resident microbiota, which comprises a diverse community of microorganisms, including bacteria, archaea, viruses, and fungi

L-Carnitine and Its Various Forms Carnitine's primary role is transporting fatty acids into the mitochondria to generate energy