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The reduced expression of GAT-1 has been suggested to occur at PV neuron terminals (Bitanihirwe and Woo, 2014), further supporting the involvement of PV neurons in the pathogenesis of schizophrenia

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The possible complementary role in the etiology of 1 of this patient's medications could explain these findings, and the histological changes associated with the drug reaction may have masked those more often found in cases of vitamin B12 deficiency

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