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Rat amylin analogs with these affinity-enhancing mutations also significantly enhanced potency for calcitonin receptor activation by 5- to 11-fold compared to endogenous rat amylin and a clinical drug pramlintide (Figure 9D and Table 3)

Once the BPC-157 is in a solution, it's no longer in a protected, dormant state

Mol Med (2008) 14:3537
