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There isnt any information about how often lipohypertrophy may happen in people using biologics for eczema
Theoretical concerns about chronic NNMT inhibition include effects on the metabolism of other quinolinium and methylpyridinium endogenous metabolites and on the broader cellular methylation landscape

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doi: 10.1007/s11325-020-02228-5

Risk increases with poor injection hygiene, reuse of needles, or injection into non-sterile sites
