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In vitro, C16-carnitine has been found to activate specific subsets of neurons in the dorsal root ganglia (DRGs) of muscles that play a key role in sensing muscle fatigue or exertion and are involved in transmitting these sensory signals to the CNS, indicating that C16-carnitine acts as a signaling molecule for muscle afferent nerves [281]

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This backbone includes a hydroxyl group (OH) on the second carbon and a carboxylic acid group (COOH) on the terminal carbon

Rating the quality of evidencestudy limitations (risk of bias) J Clin Epidemiol

46 Our recent study identified that atorvastatin reduced the level of 7-alpha-hydroxysteroid dehydrogenases (HSDH) and the conversion of CDCA to UDCA, resulting in insulin resistance 12 (Figure 2, Table 1)