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IRBPs: either a translational enhancer or a translational inhibitor, binding to iron Iron A metallic element with atomic symbol fe, atomic number 26, and atomic weight 55

10.1016/0378-8741(93)90005-P 11 AnM

Thus, enabling podocytes to overexpress OTUD5 may be a potential therapeutic strategy to delay podocyte inflammation through the OTUD5-TAK1 axis

[DOI] [PubMed] [Google Scholar] 35.Murphy JB
Importantly, both interventions increase both lifespan and healthspan without apparent major fitness trade-offs, in contrast to those previously reported in long-lived mutants that do slow the rate of ageing 39, 40