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( J Invest Dermatol ) 1999 Wound healing T4 accelerated wound closure in rodent models by promoting keratinocyte migration Philp et al

This is particularly beneficial in an era where autoimmune conditions and chronic inflammatory diseases are on the rise

Yes, and there's a good biological rationale for doing so

Cell 176, 4355.e13

The mammalian sirtuins (Sirt1--Sirt7) participate in a number of cellular and physiological functions such as gene silencing, apoptosis, mitochondrial function, energy homeostasis, and longevity [237].Transgenic mice with overexpression of the sirt1 gene demonstrate decreased lipid-induced inflammation, improved glucose tolerance, and protection from hepatic steatosis when fed a high-fat diet [238]